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  • bsm-63287R絲氨酸/蘇氨酸激酶p90RSK蛋白重組兔單抗

    Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63287R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:159
  • bsm-63286R白介素15重組兔單抗

    IL15 (114 amino acids) is a cytokine that regulates T and natural killer cell activation and proliferation. It has a predicted molecular mass of approximately 12.5 kDa. Human IL15 shares approximately 97% and 73% amino acid sequence identity with simian and mouse IL15, respectively. Both human and simian IL15 are active on mouse cells. IL15 was initially isolated from the simian kidney epithelial cell line CV1/EBNA. It has also been isolated from mouse and human cell sources. The cytokine

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63286R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:146
  • bsm-63285R磷酸化乳腺癌抗雌激素耐藥蛋白1重組兔單抗

    p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-mediated cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphory

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63285R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:171
  • bsm-63284R磷酸化IKB α重組兔單抗

    This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant diseas

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63284R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:155
  • bsm-63283R磷酸化細(xì)胞周期檢測點(diǎn)激酶1重組兔單抗

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in respons

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63283R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:159
  • bsm-63282R磷酸化微管相關(guān)蛋白重組兔單抗

    Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the

    更新時(shí)間:2025-03-05
    型號(hào):bsm-63282R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:168
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