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簡(jiǎn)要描述:This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released
產(chǎn)品型號(hào):bsm-62437R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-03-03
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